Have you tried diet and exercise but haven’t been able to lose enough weight? A prescription weight-loss drug may be a choice for you, addition to, but not instead of a healthy diet and exercise.
Adults, who have:
▪ BMI of 30 kg/m² or greater (obesity). This means you’re living with a condition that involves having too much body fat, called obesity.
▪ BMI of at least 27 kg/m² but less than 30 kg/m² (overweight) who have weight-related health problems (such as diabetes, high blood pressure, abnormal levels of fats in the blood, breathing problems during sleep called Obstructive Sleep Apnea (OSA) or a history of heart attack, stroke or blood vessel problems).
Current weight-loss drugs approved by the U.S. Food and Drug Administration (FDA) for long-term use include:
- Bupropion-naltrexone (Contrave)
- Liraglutide (Saxenda)
- Orlistat (Xenical, Alli)
- Phentermine-topiramate (Qsymia)
- Semaglutide (Wegovy)
- Setmelanotide (Imcivree)
Wegovy® is available as pre-filled pens containing a solution for injection. It is injected once a week under the skin in the abdomen, thigh or upper arm. The active ingredient in Wegovy, semaglutide, is a ‘GLP-1 receptor agonist’ that increases a person’s feelings of fullness, while reducing their food intake, hunger and cravings.
Alli® is a 60-milligram, over-the-counter version of orlistat (Xenical®), a 120-milligram prescription drug. Over-the-counter approval was controversial in the United States. After orlistat was stopped, a significant number of subjects regained weight, up to 35% of the weight they had lost.
Saxenda® (liraglutide) injection 3 mg is an injectable prescription medicine. Acute pancreatitis, including fatal and non-fatal hemorrhagic or necrotizing pancreatitis, has been observed in patients treated with liraglutide.
Contrave® contains naltrexone, an opioid antagonist, and bupropion, an aminoketone antidepressant. It is taken by mouth. Bupropion has caused some people to have suicidal thoughts or actions or unusual changes in behavior.
Qsymia® is a combination of phentermine and topiramate, to treat obesity . It is taken by mouth. Phentermine is a stimulant and appetite suppressant, while Topiramate is an anticonvulsant that has weight loss side effects.
Imcivree® contains setmelanotide, and is used for the treatment of genetic obesity caused by a rare single-gene mutation. Spontaneous penile erections in males and adverse sexual reactions in females have occurred with treatment.
Ozempic® (semaglutide) injection 0.5 mg, 1 mg, or 2 mg is an injectable prescription medicine. Gallbladder problems have happened in some people who take Ozempic.
Most common side effects in adults include nausea, diarrhea, constipation, vomiting, injection site reaction, low blood sugar (hypoglycemia), headache, tiredness (fatigue), dizziness, stomach pain, and change in enzyme (lipase) levels in your blood.
Furthermore, an oral drug (danuglipron) made by Pfizer causes a similar amount of weight loss as rival Novo Nordisk’s blockbuster injection Ozempic® (semaglutide), according to a peer-reviewed study of phase 2 clinical trial results.
Alli® 60mg (90 capsules)
Walgreens Pharmacy: $62.00
CVS Pharmacy: $79.00
Xenical® 120mg (90 capsules)
Walgreens Pharmacy: $279.30
CVS Pharmacy: $555.91
Contrave® 90mg (120 capsules)
Walgreens Pharmacy: $516.06
CVS Pharmacy: $517.06
Saxenda® 3mg/0.5ml (Five 3ml pens)
Walgreens Pharmacy: $1,595.00
CVS Pharmacy: $1,640.00
Wegovy® 0.25mg/0.5ml (Four 0.25ml pens)
CVS Pharmacy: $1,590.00
Walgreens Pharmacy: $1,619.00
CVS Pharmacy: $1,590.00
Imcivree® 10mg/ml (10 1ml vials)
CVS Pharmacy: $33,865.25
Walgreens Pharmacy: $34,063.75